Glossary · Regulation & Compliance

What Is CMR Substances?

CMR substances are ingredients classified as carcinogenic, mutagenic or toxic for reproduction under chemicals legislation. Cosmetic rules restrict or prohibit their use, generally banning CMR substances outright unless a scientific committee has assessed the specific substance as safe at a stated concentration.

Why it matters when you source

CMR status is a screening question when a formulator proposes an unusual ingredient, because the permitted concentration can be very low or zero. Ask your factory's position on the substance in writing rather than assuming a supplier declaration is sufficient.

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